Expanded primary cells
 
Human Epidermal Cells

Human Epidermal Cells

 

The epidermis is the superficial layer of the skin. Its thickness varies depending on the location, being thicker in areas exposed to frequent friction such as the palms and soles, and thinner in areas like the eyelids. It is composed of stratified, keratinized, squamous, and non-vascularized epithelial tissue. The epidermis covers the dermis, which is highly vascularized and ensures its nutrition by diffusion, as the epidermis itself lacks blood vessels. Embryologically, the epidermis originates from the ectoderm, the outermost layer of the embryo.

Constituents of the Epidermis

The main constituents of the epidermis are keratinocytes, representing about 80% of its cell population. Keratinocytes produce keratins, structural proteins critical for maintaining skin integrity, strength, and barrier function. These cells undergo a tightly regulated process of proliferation in the basal layer, followed by differentiation as they migrate upward through the layers of the epidermis, culminating in the formation of the stratum corneum — the outermost layer of dead, flattened cells that are continuously shed through desquamation.

Other key cells in the epidermis include:

  • Melanocytes: Produce melanin pigment, protecting underlying tissues from ultraviolet radiation and contributing to skin color.
  • Langerhans Cells: Immunocompetent dendritic cells involved in immune surveillance, capturing and presenting antigens to T lymphocytes.
  • Merkel Cells: Specialized mechanoreceptors responsible for the sensation of touch and pressure.

Frequently Asked Questions (FAQ)

Where can I find epidermis products on the upcyte website?

epidermis products are available in this section and can be sorted by product families or sub-categories, such as Keratinocytes. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the epidermis category?

The epidermis category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The Keratinocytes sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a epidermis product?

To find a epidermis product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does upcyte stock several product codes in the epidermis category?

Yes, upcyte distributes several product references in the epidermis category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for epidermis products?

Yes, you can request a quote for epidermis products from the product page or by contacting upcyte (info@upcyte.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a epidermis product is available to order?

The availability of a epidermis product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact upcyte with the product code or name of the product you are looking for.

What should I do if I cannot find the epidermis product I am looking for?

If the epidermis product you are looking for does not appear in the catalogue, please contact upcyte with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all epidermis products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.