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upcyte technologies – expanded primary cells

…. have you ever been concerned that your cell based assay is not relevant enough to provide you with satisfying results?
…. have you ever been forced to reduce the number of data points simply by the limitation of appropriate assay cells?

The possibility to scale up mammalian cells economically and the loss of cell-type specific properties have long been two sides of a coin. A downside which had to be accepted when assay reproducibility and throughput were obligatory needs.
upcyte technologies has managed to split this coin and is providing a solution which combines large scale cell expansion with physiological relevance. By using the proprietary upcyte® protocol non-dividing primary cells are pushed back into proliferation without altering their most relevant tissue-specific characteristics.
upcyte technologies can generate homogenous cell batches of up to 10 billion physiologically relevant cells from cell types which are otherwise limited. upcyte technologies provides assay-ready cells from various upcyted® human healthy or diseased tissues along with optimized medium formulations to make cell-based screening even more relevant and your early ADME-Tox screen more predictive.




ISSX - 20th North American Meeting

Orlando, Florida (USA) on October 18-22, 2015
Booth 209, Poster P27 & P160

Peer-reviewed publication on FXR agonists for the treatment of the Metabolic Syndrome and Non-alcoholic Steatohepatitis (NASH) link

Peer-reviewed publication about optimization of upcyte® human hepatocytes for the in vitro micronucleus assaylink 

Peer-reviewed publication about generation of proliferating human hepatocytes using upcyte® technology link

upcyte technologies GmbH

Osterfeldstraße 12-14
22529 Hamburg

Tel: +49 (0) 40/63730308


© 2015 by upcyte technologies GmbH // Osterfeldstraße 12-14 // 22529 Hamburg // Germany